@prefix this: <https://w3id.org/np/RA1axs6vCsihQW2pxW4sPQkDUPHvn6v8pT3XycUyFrVEM> .
@prefix sub: <https://w3id.org/np/RA1axs6vCsihQW2pxW4sPQkDUPHvn6v8pT3XycUyFrVEM/> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/OBI_0000066> rdfs:label "study" .
  
  <http://purl.obolibrary.org/obo/OBI_0000355> rdfs:label "hypothesis-driven investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0000356> rdfs:label "hypothesis generating investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0002897> rdfs:label "surveillance process" .
  
  <http://purl.obolibrary.org/obo/OBI_0003692> rdfs:label "case-control investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0003693> rdfs:label "observational investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0003694> rdfs:label "longitudinal investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0003695> rdfs:label "nested case-control investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0003696> rdfs:label "animal investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0003697> rdfs:label "clinical investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0003698> rdfs:label "observational clinical investigation" .
  
  <http://purl.obolibrary.org/obo/OBI_0003699> rdfs:label "clinical trial" .
  
  <http://purl.obolibrary.org/obo/OBI_0003700> rdfs:label "phase I clinical trial" .
  
  <http://purl.obolibrary.org/obo/OBI_0003701> rdfs:label "phase II clinical trial" .
  
  <http://purl.obolibrary.org/obo/OBI_0003702> rdfs:label "phase III clinical trial" .
  
  <http://purl.obolibrary.org/obo/OBI_0004001> rdfs:label "randomized clinical trial" .
  
  <http://purl.obolibrary.org/obo/OBI_0004002> rdfs:label "non-randomized clinical trial" .
  
  dct:description rdfs:label "has as description" .
  
  dct:isPartOf rdfs:label "is part of" .
  
  <http://rdf-vocabulary.ddialliance.org/discovery#Study> rdfs:label "data-collection study (DDI)" .
  
  rdf:type rdfs:label "is a" .
  
  rdfs:label rdfs:label "has the title" .
  
  rdfs:seeAlso rdfs:label "has further information at" .
  
  prov:wasAssociatedWith rdfs:label "is/was conducted by" .
  
  schema:MedicalObservationalStudy rdfs:label "medical observational study" .
  
  schema:MedicalStudy rdfs:label "medical study" .
  
  schema:MedicalTrial rdfs:label "medical trial (interventional study)" .
  
  sub:assertion a nt:AssertionTemplate;
    dct:description "Defines a scientific study, in any field of research: a planned investigation that generates knowledge, such as an experiment, an observational study, a survey, a clinical trial, or a simulation study. Give the study a short identifier and a title, and optionally pick more specific study types, describe it, link it to the project it is part of, name the people conducting it, and point to a webpage or registration with further information.";
    rdfs:label "Defining a study";
    nt:hasNanopubLabelPattern "Study: ${title}";
    nt:hasStatement sub:st0, sub:st1, sub:st2, sub:st3, sub:st4, sub:st5, sub:st6;
    nt:hasTag "Science";
    nt:hasTargetNanopubType <http://purl.obolibrary.org/obo/OBI_0000066> .
  
  sub:description a nt:LongLiteralPlaceholder;
    rdfs:label "description of the study (optional)" .
  
  sub:link a nt:UriPlaceholder;
    rdfs:label "webpage or registration with more information (optional)" .
  
  sub:person a nt:AgentPlaceholder;
    rdfs:label "who conducts or conducted the study (optional)" .
  
  sub:project a nt:ExternalUriPlaceholder, nt:GuidedChoicePlaceholder;
    rdfs:label "the project this study is part of (optional)";
    nt:possibleValuesFromApi "https://w3id.org/np/l/nanopub-query-1.1/api/RAyMrQ89RECTi9gZK5q7gjL1wKTiP8StkLy0NIkkCiyew/find-things?type=https://w3id.org/kpxl/gen/terms/Project" .
  
  sub:st0 rdf:object <http://purl.obolibrary.org/obo/OBI_0000066>;
    rdf:predicate rdf:type;
    rdf:subject sub:study .
  
  sub:st1 a nt:OptionalStatement, nt:RepeatableStatement;
    rdf:object sub:subtype;
    rdf:predicate rdf:type;
    rdf:subject sub:study .
  
  sub:st2 rdf:object sub:title;
    rdf:predicate rdfs:label;
    rdf:subject sub:study .
  
  sub:st3 a nt:OptionalStatement;
    rdf:object sub:description;
    rdf:predicate dct:description;
    rdf:subject sub:study .
  
  sub:st4 a nt:OptionalStatement;
    rdf:object sub:project;
    rdf:predicate dct:isPartOf;
    rdf:subject sub:study .
  
  sub:st5 a nt:OptionalStatement, nt:RepeatableStatement;
    rdf:object sub:person;
    rdf:predicate prov:wasAssociatedWith;
    rdf:subject sub:study .
  
  sub:st6 a nt:OptionalStatement, nt:RepeatableStatement;
    rdf:object sub:link;
    rdf:predicate rdfs:seeAlso;
    rdf:subject sub:study .
  
  sub:study a nt:IntroducedResource, nt:LocalResource, nt:UriPlaceholder;
    rdfs:label "short name for the study, used as URI suffix" .
  
  sub:subtype a nt:RestrictedChoicePlaceholder;
    rdfs:label "more specific type of study (optional)";
    nt:possibleValue <http://purl.obolibrary.org/obo/OBI_0000355>, <http://purl.obolibrary.org/obo/OBI_0000356>,
      <http://purl.obolibrary.org/obo/OBI_0002897>, <http://purl.obolibrary.org/obo/OBI_0003692>,
      <http://purl.obolibrary.org/obo/OBI_0003693>, <http://purl.obolibrary.org/obo/OBI_0003694>,
      <http://purl.obolibrary.org/obo/OBI_0003695>, <http://purl.obolibrary.org/obo/OBI_0003696>,
      <http://purl.obolibrary.org/obo/OBI_0003697>, <http://purl.obolibrary.org/obo/OBI_0003698>,
      <http://purl.obolibrary.org/obo/OBI_0003699>, <http://purl.obolibrary.org/obo/OBI_0003700>,
      <http://purl.obolibrary.org/obo/OBI_0003701>, <http://purl.obolibrary.org/obo/OBI_0003702>,
      <http://purl.obolibrary.org/obo/OBI_0004001>, <http://purl.obolibrary.org/obo/OBI_0004002>,
      <http://rdf-vocabulary.ddialliance.org/discovery#Study>, schema:MedicalObservationalStudy,
      schema:MedicalStudy, schema:MedicalTrial .
  
  sub:title a nt:LiteralPlaceholder;
    rdfs:label "title of the study" .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1267-0234 .
}

sub:pubinfo {
  orcid:0000-0002-1267-0234 foaf:name "Tobias Kuhn" .
  
  this: dct:created "2026-09-24T09:38:44+00:00"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1267-0234;
    dct:license <https://creativecommons.org/licenses/by/4.0/>;
    npx:supersedes <https://w3id.org/np/RAWaGj1HOf1_9D-zgvejQ3GCcCIFu4qBArSYKguPU0r5Y>;
    rdfs:label "Defining a study";
    skos:changeNote "Guided choices that must refer to existing resources are now also external URI placeholders, so Nanodash no longer offers to mint a typed plain name locally for them: project.";
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <https://w3id.org/np/RA0J4vUn_dekg-U1kK3AOEt02p9mT2WO03uGxLDec1jLw>,
      <https://w3id.org/np/RAKc76yHLDbloE6ObluzYQsfX37v6qrZXbYeIKpe8-YUo>, <https://w3id.org/np/RAoTD7udB2KtUuOuAe74tJi1t3VzK0DyWS7rYVAq1GRvw>,
      <https://w3id.org/np/RAukAcWHRDlkqxk7H2XNSegc1WnHI569INvNr-xdptDGI>;
    nt:wasCreatedFromTemplate <https://w3id.org/np/RA1XuAdO6LOtlPJgWiytJHFuK4BFHjQK5x7d9FVymzFnc> .
  
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCwUtewGCpT5vIfXYE1bmf/Uqu1ojqnWdYxv+ySO80ul8Gu7m8KoyPAwuvaPj0lvPtHrg000qMmkxzKhYknEjq8v7EerxZNYp5B3/3+5ZpuWOYAs78UnQVjbHSmDdmryr4D4VvvNIiUmd0yxci47dTFUj4DvfHnGd6hVe5+goqdcwIDAQAB";
    npx:hasSignature "KeqTP/6l4VALVioU9WuBMtPugr8U7tSOtp1sO/A2F7oWB91lUHuzy4VYw41UCqFQjWUzZJfOtFNN7LeveOSyWhrLJY5hJryDF8ymON47ynH1pIHq6ywXLEKmZtI1hsTt2iUcngnbdJwWaK4RIbl9sjOimdt4a2AsSQlkcPgvfqs=";
    npx:hasSignatureTarget this:;
    npx:signedBy orcid:0000-0002-1267-0234 .
}