http://purl.org/np/RA3-5n-wsBtW7Cs6aHHM0w45zn-KkpfyGGx8nDhJONYFU
.trig | .trig.txt | .jelly | .jelly.txt
@prefix this: <http://purl.org/np/RA3-5n-wsBtW7Cs6aHHM0w45zn-KkpfyGGx8nDhJONYFU> .
@prefix sub: <http://purl.org/np/RA3-5n-wsBtW7Cs6aHHM0w45zn-KkpfyGGx8nDhJONYFU#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix unii: <http://identifiers.org/unii/> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
this: a np:Nanopublication;
np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubInfo .
}
sub:assertion {
<http://identifiers.org/pubchem.compound/2907> a biolink:ChemicalEntity;
rdfs:label "cyclophosphamide";
biolink:category biolink:ChemicalEntity .
<http://identifiers.org/pubchem.compound/49841217> a biolink:ChemicalEntity;
rdfs:label "Avacopan";
biolink:category biolink:ChemicalEntity .
unii:4F4X42SYQ6 a biolink:ChemicalEntity;
rdfs:label "rituximab";
biolink:category biolink:ChemicalEntity .
<http://purl.obolibrary.org/obo/CHEBI_165825> a biolink:DiseaseOrPhenotypicFeature;
rdfs:label "GPA";
biolink:category biolink:DiseaseOrPhenotypicFeature .
<http://purl.obolibrary.org/obo/CHEBI_24261> a biolink:ChemicalEntity;
rdfs:label "glucocorticoids";
biolink:category biolink:ChemicalEntity .
<http://purl.obolibrary.org/obo/MONDO_0012105> a biolink:DiseaseOrPhenotypicFeature;
rdfs:label "granulomatosis with polyangiitis";
biolink:category biolink:DiseaseOrPhenotypicFeature .
<http://purl.obolibrary.org/obo/MONDO_0018882> a biolink:DiseaseOrPhenotypicFeature;
rdfs:label "polyang.itis", "vasculitis";
biolink:category biolink:DiseaseOrPhenotypicFeature .
<http://purl.obolibrary.org/obo/MONDO_0019124> a biolink:DiseaseOrPhenotypicFeature;
rdfs:label "MPA";
biolink:category biolink:DiseaseOrPhenotypicFeature .
sub:_1 a biolink:Association;
rdf:object <http://identifiers.org/pubchem.compound/2907>;
rdf:predicate biolink:interacts_with;
rdf:subject <http://identifiers.org/pubchem.compound/49841217>;
biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
biolink:category biolink:Association;
biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
sub:_2 a biolink:Association;
rdf:object <http://purl.obolibrary.org/obo/MONDO_0018882>;
rdf:predicate biolink:treats;
rdf:subject <http://identifiers.org/pubchem.compound/49841217>;
biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
biolink:category biolink:Association;
biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
sub:_3 a biolink:Association;
rdf:object <http://purl.obolibrary.org/obo/MONDO_0012105>;
rdf:predicate biolink:treats;
rdf:subject <http://identifiers.org/pubchem.compound/49841217>;
biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
biolink:category biolink:Association;
biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
sub:_4 a biolink:Association;
rdf:object unii:4F4X42SYQ6;
rdf:predicate biolink:interacts_with;
rdf:subject <http://identifiers.org/pubchem.compound/49841217>;
biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
biolink:category biolink:Association;
biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
sub:_5 a biolink:Association;
rdf:object <http://purl.obolibrary.org/obo/CHEBI_24261>;
rdf:predicate biolink:treats;
rdf:subject <http://identifiers.org/pubchem.compound/49841217>;
biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
biolink:category biolink:Association;
biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
sub:_6 a biolink:Association;
rdf:object <http://purl.obolibrary.org/obo/MONDO_0019124>;
rdf:predicate biolink:treats;
rdf:subject <http://identifiers.org/pubchem.compound/49841217>;
biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
biolink:category biolink:Association;
biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
}
sub:provenance {
sub:assertion prov:generatedAtTime "2022-10-13T13:48:59.639916"^^xsd:dateTime;
prov:wasAttributedTo orcid:0000-0002-3668-2627;
prov:wasQuotedFrom " Avacopan is indicated for the adjunctive treatment of adult patients with severe active anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (granulomatosis with polyangiitis) in combination with standard therapy including glucocorticoids. In Europe, it is approved for the. treatment of adults with severe, active granulomatic polyang.itis (GPA/MPA) in. combination with rituximab or cyclophosphamide." .
biolink: pav:version "2.3.0" .
}
sub:pubInfo {
sub:sig npx:hasAlgorithm "RSA";
npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEApdULbl+/+pkVlq0fAzWmzfgIb+XMuQPKHMDVzUTWCZBjLfzORll42ptr52e4w7tTYkUKrBsQbx8lkjZWAlWiyh+xIK0oLFSdYRSt63kgiyRYBUOR+spcgmofb7f6JyftArPVTKhsWOMt/mcyNG9qc3lw8B/xuPmLteUWO33xWhfXQreTw1lsGUkZ1j4cB4X9HIuI20ktLYLCXaBauNHEJZ4qp6/Q2ATsJcw8tg7aRmFKXhrjM9maZ2+0cMg0Jpmn2UnDlPKXEA6Qq+qnvvQt8KFjIzP9FTMyvrWl8tTd0NCmS9VpooZJQ8We1lGMPXg5bMbe/bVkTf70fbFMf0RKrQIDAQAB";
npx:hasSignature "mktsnL/cZhj07z6wkSISbggRQl4OJRgJOTb1UQiJzMrPsxgZLsHOQvCSksUB+WEpLq9UbVxLu0J1Nzf1iwcFvaAzAxMBcY4UEb8kQrelTbAw9UsMHVnPx2b4Tn/QCnPgWf1opk2oeQpzg2leyDCEAopID/stcZCofHpKW4+nR8HxRiSb/uJyfpxnNAQnu/4+09ymLH20D5r7FLo/7bJGgEIMNYngG+GCQj5aP6KCl4KOZUPqBmX7PocF4yR4j279dKE0t6kg8vzXAJqSEo0d+d0DvTEtZoLXleGBj83eq09PfUwffeMSdvfweVIncxGmJ/f7f+zDcHgO5WM6qWVOxA==";
npx:hasSignatureTarget this: .
this: prov:generatedAtTime "2022-10-13T13:48:59.639916"^^xsd:dateTime;
prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}