@prefix this: <https://pd.sciai.eu/np/1876251/RA3kX2lkQdK6WocWdXr73JKAM7zuz9pikei3y213QYgyw> .
@prefix sub: <https://pd.sciai.eu/np/1876251/RA3kX2lkQdK6WocWdXr73JKAM7zuz9pikei3y213QYgyw/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  sub:claim a <https://pd.sciai.eu/ontology/property/Assertion>;
    <https://pd.sciai.eu/ontology/property/assertionId> "1876251"^^xsd:integer;
    <https://pd.sciai.eu/ontology/property/confidence> "0.85"^^xsd:decimal;
    <https://pd.sciai.eu/ontology/property/effectDirection> "negative";
    <https://pd.sciai.eu/ontology/property/evidenceTier> "3"^^xsd:integer;
    <https://pd.sciai.eu/ontology/property/hasObject> <https://pd.sciai.eu/ontology/entity/D000071679>;
    <https://pd.sciai.eu/ontology/property/hasRelation> <https://pd.sciai.eu/ontology/relation/inhibits>;
    <https://pd.sciai.eu/ontology/property/hasSubject> <https://pd.sciai.eu/ontology/entity/CLU%3Api3k-akt-signaling-pathway-2> .
  
  <https://pd.sciai.eu/ontology/entity/CLU%3Api3k-akt-signaling-pathway-2> a <https://pd.sciai.eu/ontology/type/Pathway>;
    <http://www.w3.org/2000/01/rdf-schema#label> "PI3K/Akt pathway";
    <https://pd.sciai.eu/ontology/relation/inhibits> <https://pd.sciai.eu/ontology/entity/D000071679> .
  
  <https://pd.sciai.eu/ontology/entity/D000071679> a <https://pd.sciai.eu/ontology/type/Protein>;
    <http://www.w3.org/2000/01/rdf-schema#label> "GSK3β" .
}

sub:provenance {
  sub:assertion <http://www.w3.org/2000/01/rdf-schema#comment> "Evidence-state label of the citing paper within the GLP-1 pilot corpus (207 papers; supported / contested / single-source / unlabeled), computed from cross-paper agreement over kg.assertions with author-overlap independence exclusions (v2, 2026-09-21).";
    prov:wasDerivedFrom <https://pubmed.ncbi.nlm.nih.gov/42311464/>;
    prov:wasGeneratedBy <https://sciai.eu/#sciai-lab>;
    <https://pd.sciai.eu/ontology/property/evidenceStateLabel> "supported";
    <https://pd.sciai.eu/ontology/property/extractedAt> "2026-09-07T05:17:12.749026+00:00"^^xsd:dateTime;
    <https://pd.sciai.eu/ontology/property/extractionSchema> "universal_pd_v4";
    <https://pd.sciai.eu/ontology/property/paperType> "narrative_review";
    <https://pd.sciai.eu/ontology/property/verbatimContext> "Akt inhibits GSK-3β, reducing tau hyperphosphorylation." .
}

sub:pubinfo {
  this: dc:created "2026-11-06T23:32:25+00:00"^^xsd:dateTime;
    dc:creator <https://pd.sciai.eu/np/bot/sciai-kg-publisher>;
    dc:license <https://creativecommons.org/licenses/by-sa/4.0/>;
    <http://www.w3.org/2000/01/rdf-schema#comment> "Machine-generated by the sciai-lab KG publisher bot (https://pd.sciai.eu/np/bot/sciai-kg-publisher) from the sciai-lab knowledge graph (kg.assertions); not manually authored. Responsible contact: Johannes Keizer (https://orcid.org/0009-0008-6409-2596).";
    prov:wasAttributedTo <https://sciai.eu/#sciai-lab> .
  
  sub:sig npx:hasAlgorithm "RSA";
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    npx:hasSignature "fkht3rjHDulGgoO9YaT+tUZ3sw5FAZqBCnA+8kCGWAdFypjwFZahxOJALNw2kexK00wDOLuBpw5BnLXuiM2tU+AmQE3429kIRrN2tGFXYihGIv0yi0qWzgAgeQJkthKbkeg+4Xl+PFDfhPI8CD7j2Rs04q2xBG/LbUTB7pXrLQg5wjxw0el2bClPVmzLCTyg6gtkK9yu9NLgVK+bJezTMN2O1OBV4NC+MKDY+a4ivWO0zUeYSNpBNzB5sVHmZcD66zRnAR4SAT/iZsqf7Nqvn8CXeMv5EHVkIi4rcmt9ZHkJzTL1ImG6RwFTq7VrXySjwqGi+vYi82ZOjXrBGN+iWw==";
    npx:hasSignatureTarget this:;
    npx:signedBy <https://pd.sciai.eu/np/bot/sciai-kg-publisher> .
}