@prefix this: <https://pd.sciai.eu/np/2500807/RAF1G8yPaO35Wv9zmhB67i-FN8p0_YHDfp5t4svGWPAGw> .
@prefix sub: <https://pd.sciai.eu/np/2500807/RAF1G8yPaO35Wv9zmhB67i-FN8p0_YHDfp5t4svGWPAGw/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  sub:claim a <https://pd.sciai.eu/ontology/property/Assertion>;
    <https://pd.sciai.eu/ontology/property/assertionId> "2500807"^^xsd:integer;
    <https://pd.sciai.eu/ontology/property/confidence> "0.85"^^xsd:decimal;
    <https://pd.sciai.eu/ontology/property/effectDirection> "positive";
    <https://pd.sciai.eu/ontology/property/evidenceTier> "3"^^xsd:integer;
    <https://pd.sciai.eu/ontology/property/hasObject> <https://pd.sciai.eu/ontology/entity/CLU%3Acamp-pka-signaling-pathway>;
    <https://pd.sciai.eu/ontology/property/hasRelation> <https://pd.sciai.eu/ontology/relation/activates>;
    <https://pd.sciai.eu/ontology/property/hasSubject> <https://pd.sciai.eu/ontology/entity/D000067757> .
  
  <https://pd.sciai.eu/ontology/entity/CLU%3Acamp-pka-signaling-pathway> a <https://pd.sciai.eu/ontology/type/Pathway>;
    <http://www.w3.org/2000/01/rdf-schema#label> "cAMP-PKA pathway" .
  
  <https://pd.sciai.eu/ontology/entity/D000067757> a <https://pd.sciai.eu/ontology/type/Protein>;
    <http://www.w3.org/2000/01/rdf-schema#label> "GLP-1 receptor";
    <https://pd.sciai.eu/ontology/relation/activates> <https://pd.sciai.eu/ontology/entity/CLU%3Acamp-pka-signaling-pathway> .
}

sub:provenance {
  sub:assertion <http://www.w3.org/2000/01/rdf-schema#comment> "Evidence-state label of the citing paper within the GLP-1 pilot corpus (207 papers; supported / contested / single-source / unlabeled), computed from cross-paper agreement over kg.assertions with author-overlap independence exclusions (v2, 2026-09-21).";
    prov:wasDerivedFrom <https://pubmed.ncbi.nlm.nih.gov/42121905/>;
    prov:wasGeneratedBy <https://sciai.eu/#sciai-lab>;
    <https://pd.sciai.eu/ontology/property/evidenceStateLabel> "supported";
    <https://pd.sciai.eu/ontology/property/extractedAt> "2026-09-07T05:17:32.123070+00:00"^^xsd:dateTime;
    <https://pd.sciai.eu/ontology/property/extractionSchema> "universal_pd_v5";
    <https://pd.sciai.eu/ontology/property/paperType> "narrative_review";
    <https://pd.sciai.eu/ontology/property/verbatimContext> "GLP-1R activation stimulates adenylate cyclase, increasing cAMP levels and PKA activity." .
}

sub:pubinfo {
  this: dc:created "2026-11-06T23:32:25+00:00"^^xsd:dateTime;
    dc:creator <https://pd.sciai.eu/np/bot/sciai-kg-publisher>;
    dc:license <https://creativecommons.org/licenses/by-sa/4.0/>;
    <http://www.w3.org/2000/01/rdf-schema#comment> "Machine-generated by the sciai-lab KG publisher bot (https://pd.sciai.eu/np/bot/sciai-kg-publisher) from the sciai-lab knowledge graph (kg.assertions); not manually authored. Responsible contact: Johannes Keizer (https://orcid.org/0009-0008-6409-2596).";
    prov:wasAttributedTo <https://sciai.eu/#sciai-lab> .
  
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEAmbH3DJ0b7gHODI7sDgcVyu5oU1CCZ/ExuejhS0LiNfnjx6SFzKWZDYEvakKaDFZUNkoFzdjVVhBZfV6MKxv3Jh8xzq876JjGkFoNqIO6tUTmMtkpP2eS26/QTPuoAn4psuSIgNCvAk/98cL1wpWS9kl/WNb+1L7RL8mrN72f0P3we555ShsIRgHD8hQJM3cK/naK4JBm350q1nzfUYLhMHUriRlJyXw7JbRnpAAlKCvoIvU4a9X5XM3ULr9ochcIlw7HgZdqD/hrL6CX0c+s0huvKK9SWTkcsO1Xp4oacwUlgPVYFg7OQiyB/WOIV7iXhYlP92s0+KSqX8XJoU2jCQIDAQAB";
    npx:hasSignature "MDGOYous/UwwZZUxB7YEy1OfpoyJu/rfOfTAHkWi1Co0Q8e4Fshsov6yWFYbQKDD3P2b+QaL+OW5NCgW5jTNX69WKHekb/P+WPF9StmRIipIv6oG05mvjB2nFo45EDfdYF9yXGfvZ54K9NYU5vTaGtQEWGkjqJf4EppY9bFc7oSQAuEgdAmhHCEwmmG8sfKRy8WmGEaQJuK1RXalDkcqnQGejySPnCuprUPPlr776gD+kyxngLNzV6OBbMR/5xq9vXnyfFn0VG7gxwkaYrLaCO2AAJfGQFjbTTVSUsdni3oaO5RPROh1Sw4ix/HWIRuYRwvAdM8lR1vAlDsX3GJlLw==";
    npx:hasSignatureTarget this:;
    npx:signedBy <https://pd.sciai.eu/np/bot/sciai-kg-publisher> .
}