@prefix this: <http://purl.org/np/RAIm6t-GCskebgwkveeYnpaHe8C5_V_BzvdoIiWDB9NDs> .
@prefix sub: <http://purl.org/np/RAIm6t-GCskebgwkveeYnpaHe8C5_V_BzvdoIiWDB9NDs#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo .
}

sub:assertion {
  <http://identifiers.org/pubchem.compound/10184665> a biolink:ChemicalEntity;
    rdfs:label "Vilanterol";
    biolink:category biolink:ChemicalEntity .
  
  <http://identifiers.org/pubchem.compound/71306415> a biolink:ChemicalEntity;
    rdfs:label "ELLIPTA";
    biolink:category biolink:ChemicalEntity .
  
  <http://identifiers.org/pubchem.compound/9854489> a biolink:ChemicalEntity;
    rdfs:label "Fluticasone Furoate";
    biolink:category biolink:ChemicalEntity .
  
  umls:C0034067 a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "emphysema";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  umls:C0741804 a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "acute bronchospasm";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0005002> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "airflow obstruction", "chronic obstructive pulmonary disease";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0005607> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "chronic bronchitis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0011751> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "COPD";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  sub:_1 a biolink:Association;
    rdf:object umls:C0034067;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/71306415>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_10 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0011751>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/9854489>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_11 a biolink:Association;
    rdf:object <http://identifiers.org/pubchem.compound/71306415>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/10184665>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_12 a biolink:Association;
    rdf:object umls:C0034067;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/10184665>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_13 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005607>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/10184665>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_14 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/71306415>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_15 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/10184665>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_16 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/71306415>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_17 a biolink:Association;
    rdf:object umls:C0034067;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/9854489>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_18 a biolink:Association;
    rdf:object umls:C0741804;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/10184665>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_19 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005607>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/9854489>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_2 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005607>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/71306415>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_3 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/10184665>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_4 a biolink:Association;
    rdf:object umls:C0741804;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/71306415>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_5 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/9854489>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_6 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0011751>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/10184665>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_7 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0011751>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/71306415>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_8 a biolink:Association;
    rdf:object umls:C0741804;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/9854489>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
  
  sub:_9 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/9854489>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40483372-448f-4284-976c-8462ef256661> .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-10T15:19:49.777614"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom " Fluticasone Furoate/Vilanterol ELLIPTA 100/25 mcg is indicated for the long-term, once-daily, maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. The drug is NOT indicated for relief of acute bronchospasm." .
  
  biolink: pav:version "2.3.0" .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEApdULbl+/+pkVlq0fAzWmzfgIb+XMuQPKHMDVzUTWCZBjLfzORll42ptr52e4w7tTYkUKrBsQbx8lkjZWAlWiyh+xIK0oLFSdYRSt63kgiyRYBUOR+spcgmofb7f6JyftArPVTKhsWOMt/mcyNG9qc3lw8B/xuPmLteUWO33xWhfXQreTw1lsGUkZ1j4cB4X9HIuI20ktLYLCXaBauNHEJZ4qp6/Q2ATsJcw8tg7aRmFKXhrjM9maZ2+0cMg0Jpmn2UnDlPKXEA6Qq+qnvvQt8KFjIzP9FTMyvrWl8tTd0NCmS9VpooZJQ8We1lGMPXg5bMbe/bVkTf70fbFMf0RKrQIDAQAB";
    npx:hasSignature "WdDi1hc8oywbfDoJPAckQbicxZxTx/PYCbxLg3O3AIB7uI8KMqErrKECwTCbx1RHtMkgC0vXTbYqunb2Vu9Qs99+OAl+wa09pgC9yMFRKpl77LyhLuaE6lxjUwQKbqauRtNgRpLOCLH8N+apMgzkd7m5KUb1hQj5IIhidCCTI4rD/amxQ8HgF7hCUX2sFiwvTmwKohp4js62+zH875mRvKYeFHzF8qod6h/w+lXbLD5I+zc9ErSTQPnm4YhqCVtg32OF0jgAk5CEPLbdGxcNAyDSZ9YASPgSggMkOD/lt0bgLMIBtsSkKn/lOoeP0ojcZ+47xCxv5YNBKwgMe5JnJw==";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2022-10-10T15:19:49.777614"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}