@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAStRuG2TC8tk3ff6If3504yWIwUTwvH8qZO-O7V18A7A> .
@prefix sub: <http://purl.org/np/RAStRuG2TC8tk3ff6If3504yWIwUTwvH8qZO-O7V18A7A#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9203> biolink:category biolink:Disease .
  
  sub:association a rdf:Statement;
    rdf:object <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9203>;
    rdf:predicate biolink:treats;
    rdf:subject <https://identifiers.org/CHEBI:119915>;
    rdfs:label "ABSTRAL® is indicated for the management of breakthrough pain in cancer patients 18 years of age and older who are already receiving, and who are tolerant to, around-the-clock opioid therapy for their underlying persistent cancer pain.";
    biolink:association_type biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    biolink:has_population_context sub:cohort;
    biolink:provided_by <https://w3id.org/um/NeuroDKG>;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e60f00e9-2cf4-4c20-b570-1c2ea426c8c7>;
    biolink:relation schema:TreatmentIndication .
  
  sub:cohort rdfs:label "in cancer patients 18 years of age and older";
    schema:requiredMinAge "18";
    biolink:category biolink:Cohort;
    biolink:has_phenotype <https://identifiers.org/MONDO:0005070> .
  
  <https://identifiers.org/CHEBI:119915> biolink:category biolink:Drug .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "GFGdoa+Dvg/NF7sXwCdUcm6zr8PznjOXsWnIcOEvPYMO+uKt1ClF4U4POL73DDf9/DZ/DIi1ZpqvCZVEOYbT71sfsFzP6lGfFvGgGZZElHIRz+hm4ONxwmKPkBcNrMgGLaA1kOVslvKUa+gqBQr43Q4GMCwyL4ZQFJr6hcQMW34=";
    npx:hasSignatureTarget this: .
  
  this: dcterms:created "2021-04-12T09:15:24.446+02:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAZdZj78B6nKrP1Q00oFzsK07u7WdiY3sToz-H-H2nSgg> .
}