@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix sp: <https://w3id.org/linkflows/superpattern/terms/> .
@prefix this: <http://purl.org/np/RAXkuXJ4IK10Ai9F39_tOFDy6ewi7znau6OQhUEXP4nPc> .
@prefix sub: <http://purl.org/np/RAXkuXJ4IK10Ai9F39_tOFDy6ewi7znau6OQhUEXP4nPc#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  sub:spi a sp:SuperPatternInstance;
    rdfs:label "The protein TDP-43 represses cryptic exon inclusion in the gene UNC13A.";
    sp:hasContextClass <http://www.wikidata.org/entity/Q18036664>;
    sp:hasObjectClass <http://purl.obolibrary.org/obo/VariO_0504>;
    sp:hasQualifier sp:generallyQualifier;
    sp:hasRelation sp:inhibits;
    sp:hasSubjectClass <http://www.wikidata.org/entity/Q21133247> .
}

sub:provenance {
  sub:activity a sp:FormalizationActivity;
    prov:used sub:quote, <https://www.biorxiv.org/content/10.1101/2021.04.02.438213v1>;
    prov:wasAssociatedWith orcid:0000-0003-2310-3013 .
  
  sub:assertion prov:wasGeneratedBy sub:activity .
  
  sub:quote prov:value "Here we show that TDP-43 represses a cryptic exon splicing event in UNC13A.";
    prov:wasQuotedFrom <https://www.biorxiv.org/content/10.1101/2021.04.02.438213v1> .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCKr8mDKqduV4sU41GiCvB3R8Hrv3cdc+FxyCD0iONSayErC8oLDfaMBKZSLMkPBapyXeAjWbYmhuey7COxiakpTqSGKzy8AnMKNZ7tgd3KATKBPLQiawisIxx0BFpxw50yA2spZhv2bEpdni9wUOGa1MG+0sKC6bo2DnjxxxeA/wIDAQAB";
    npx:hasSignature "PBzoLld6dCDC9ZgL1KNN0L2bEiH1Z7MpIHnpGlhKKV7YqsrlFL9pS6z6mtMTrdfZwSqupg1o2pwWluWqIzindCa8rTEVzcQAOrEvFP/Xg0yef/f7lDeVrvyVZDxhhgWULwH8hesWGqhWgY0cLlmGsXtS4ft5GVU7o60AO5HMCAM=";
    npx:hasSignatureTarget this: .
  
  this: dct:created "2021-10-26T13:03:28.286Z"^^xsd:dateTime;
    dct:creator orcid:0000-0003-2310-3013;
    npx:introduces sub:spi;
    <https://w3id.org/linkflows/reviews/isUpdateOf> <http://purl.org/np/RAIWvdnjqmOl2VP_eR2oFBxk97A_dw__FeusMzuRE9SIY>;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RAE1wniOy0yO39PlK9QkQ-wqbC3q-R2nXraP5huu8W39k>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>,
      <http://purl.org/np/RAOGu9Lh0BD4tbIRB9RG6RGRA_ObDh75NTbIqaWgxxs8M>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAv68imZrEjfcp2rnEg1hzoBqEVc0cQMtp9_1Za0BxNM4> .
}