@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RA_b4CBVFPDfQXNn4W-bKnkOLksphW_tWhaHxzwfEEww4> .
@prefix sub: <http://purl.org/np/RA_b4CBVFPDfQXNn4W-bKnkOLksphW_tWhaHxzwfEEww4#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix orcid: <https://orcid.org/> .
@prefix nkg: <https://w3id.org/neurodkg/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_6364> schema:possibleTreatment sub:medtherapy .
  
  sub:medtherapy prov:wasDerivedFrom sub:quote;
    schema:drug <http://identifiers.org/drugbank/DB00273>;
    schema:targetPopulation sub:targetpop;
    nkg:indicationType schema:PreventionIndication .
  
  sub:quote prov:value "Topiramate tablets and topiramate capsules are indicated for the preventive treatment of migraine in patients 12 years of age and older";
    prov:wasQuotedFrom <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6f9d59e3-d10d-48f3-af01-83ba3e1e3a2b> .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "VkYX2qXfV0MCVixdbAlX1FDgw1Aj6ppgm6IutSCbdw2BJPnmAH+m201y8Rrmn6vkNxJQ5TQ9enlm08UlDICDVLQ3SEu5Kz/FPB7tTMSOWO2mG6Bxs/gpa7oRJQhKdKMHUdU5zdoCGM3bcJ/HuXGKbmCwCYCC+bpEg5GsLOwq0Zo=";
    npx:hasSignatureTarget this: .
  
  this: dcterms:created "2021-04-03T10:40:32.996+02:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RA64ptuigOfVGfIhpdwWeJnssaHV9jTQCnAm6Pvgrvmos> .
}