Each vancomycin-resistant Enterococcus faecium isolate pair with a potential epidemiological link was classified as unrelated, clonal, plasmid-mediated or mixed, combining sequence clusters, Tn1546 variants and predicted plasmids. On average 59% of pairs were unrelated, 32% clonal, 7% plasmid-mediated and 2% mixed, across 309 isolates from 32 Dutch hospitals (2012-2015).
Pairwise dissemination-mode classification
Evidence: Pairwise dissemination-mode classification