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This dataset contains molecular dynamic simulation data of Loxosceles phospholipase D enzymes, of both clades, in presence of different bilayer compositions. The enzymes simulated are Li_alphaIA1, St_beta1B1, Ll_alphaIII and R44Y/S60Y St_beta1B1. The bilayers are used are a pure POPC, PC:SM:CHOL (70:20:10) and POPC:POPE (50:50) bilayer. The trajectories are in DCD format and the topology file in PSF format.The following simulations are available:
1. Li_alphaIA1 on a pure POPC bilayer;
2. Li_alphaIA1 on a PC:SM:CHOL (70:20:10) bilayer;
3. Li_alphaIA1 on a POPC:POPE (50:50) bilayer;
4. Ll_alphaIII on a pure POPC bilayer;
5. Ll_alphaIII on a PC:SM:CHOL (70:20:10) bilayer;
6. R44Y/S60Y St_beta1B1 on a pure POPC bilayer;
7. St_beta1B1 on a pure POPC bilayer;
8. St_beta1B1 on a PC:SM:CHOL (70:20:10) bilayer;
9. St_beta1B1 on a POPC:POPE (50:50) bilayer;
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Specificity of Loxosceles alpha clade phospholipase D enzymes for choline-containing lipids: role of a conserved aromatic cage
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Specificity of Loxosceles alpha clade phospholipase D enzymes for choline-containing lipids: role of a conserved aromatic cage.
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The bilayers are used are a pure POPC, PC:SM:CHOL (70:20:10) and POPC:POPE (50:50) bilayer.
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This dataset contains molecular dynamic simulation data of Loxosceles phospholipase D enzymes, of both clades, in presence of different bilayer compositions.
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Emmanuel Moutoussamy. "Specificity of Loxosceles alpha clade phospholipase D enzymes for choline-containing lipids: role of a conserved aromatic cage." ROHub. Mar 22 ,2022. https://w3id.org/ro-id/d5486b94-4c58-4cb4-8b1e-6945adf5eba9.
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Moutoussamy, E. (2021).Specificity of Loxosceles alpha clade phospholipase D enzymes for choline-containing lipids: role of a conserved aromatic cage [Data set]. Norstore. https://doi.org/10.11582/2021.00099
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Nathalie Reuter
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This dataset contains molecular dynamic simulation data of Loxosceles phospholipase D enzymes, of both clades, in presence of different bilayer compositions. The enzymes simulated are Li_alphaIA1, St_beta1B1, Ll_alphaIII and R44Y/S60Y St_beta1B1. The bilayers are used are a pure POPC, PC:SM:CHOL (70:20:10) and POPC:POPE (50:50) bilayer. The trajectories are in DCD format and the topology file in PSF format.The following simulations are available:
1. Li_alphaIA1 on a pure POPC bilayer;
2. Li_alphaIA1 on a PC:SM:CHOL (70:20:10) bilayer;
3. Li_alphaIA1 on a POPC:POPE (50:50) bilayer;
4. Ll_alphaIII on a pure POPC bilayer;
5. Ll_alphaIII on a PC:SM:CHOL (70:20:10) bilayer;
6. R44Y/S60Y St_beta1B1 on a pure POPC bilayer;
7. St_beta1B1 on a pure POPC bilayer;
8. St_beta1B1 on a PC:SM:CHOL (70:20:10) bilayer;
9. St_beta1B1 on a POPC:POPE (50:50) bilayer;
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