SARS-CoV-2 Spike RBD variant Alpha, carrying the N169Y substitution (corresponding to N501Y in the full Spike numbering). Pango lineage B.1.1.7. Designated a Variant of Concern (VOC) by the WHO. RBD anchor FDO for the MAC FAIR Digital Twin observation cluster — all Type 2-8 observation FDOs of this variant link back here via mac:isObservationOf.