Nanopublication

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ID

http://purl.org/np/RApHsKFnbSdWEl86GviCOj-qg9IDUR9AvvMRF8bO4DHLU

Formats

.trig | .trig.txt | .jelly | .jelly.txt

Content

@prefix this: <http://purl.org/np/RApHsKFnbSdWEl86GviCOj-qg9IDUR9AvvMRF8bO4DHLU> .
@prefix sub: <http://purl.org/np/RApHsKFnbSdWEl86GviCOj-qg9IDUR9AvvMRF8bO4DHLU#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo .
}

sub:assertion {
  <http://identifiers.org/ncbigene/3949> a biolink:ChemicalEntity;
    rdfs:label "LDL";
    biolink:category biolink:ChemicalEntity .
  
  <http://identifiers.org/pubchem.compound/5997> a biolink:ChemicalEntity;
    rdfs:label "cholesterol";
    biolink:category biolink:ChemicalEntity .
  
  <http://identifiers.org/pubchem.compound/60823> a biolink:ChemicalEntity;
    rdfs:label "Atorvastatin";
    biolink:category biolink:ChemicalEntity .
  
  umls:C0570410 a biolink:ChemicalEntity;
    rdfs:label "Statins", "statins";
    biolink:category biolink:ChemicalEntity .
  
  <http://purl.obolibrary.org/obo/MONDO_0002525> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "dyslipidemia";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0004995> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "CVD", "cardiovascular diseases";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  sub:_1 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0004995>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/60823>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ae7c54b1-b440-4cca-97e8-e5b825413d32> .
  
  sub:_2 a biolink:Association;
    rdf:object <http://identifiers.org/pubchem.compound/5997>;
    rdf:predicate biolink:associated_with;
    rdf:subject <http://purl.obolibrary.org/obo/MONDO_0004995>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ae7c54b1-b440-4cca-97e8-e5b825413d32> .
  
  sub:_3 a biolink:Association;
    rdf:object <http://purl.obolibrary.org/obo/MONDO_0002525>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/60823>;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ae7c54b1-b440-4cca-97e8-e5b825413d32> .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-13T12:35:21.230396"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom " Atorvastatin and other statins are considered first-line treatment options for dyslipidemia. The increasing use of this class of drugs is largely attributed to the rise in cardiovascular diseases (CVD) An elevated cholesterol level (elevated low-density lipoprotein (LDL) levels) is a significant risk factor for the development of CVD. Statins were shown to reduce the incidences of all-cause mortality, including fatal and non-fatal CVD, as well as the need for surgical revascularization or angioplasty following a" .
  
  biolink: pav:version "2.3.0" .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEApdULbl+/+pkVlq0fAzWmzfgIb+XMuQPKHMDVzUTWCZBjLfzORll42ptr52e4w7tTYkUKrBsQbx8lkjZWAlWiyh+xIK0oLFSdYRSt63kgiyRYBUOR+spcgmofb7f6JyftArPVTKhsWOMt/mcyNG9qc3lw8B/xuPmLteUWO33xWhfXQreTw1lsGUkZ1j4cB4X9HIuI20ktLYLCXaBauNHEJZ4qp6/Q2ATsJcw8tg7aRmFKXhrjM9maZ2+0cMg0Jpmn2UnDlPKXEA6Qq+qnvvQt8KFjIzP9FTMyvrWl8tTd0NCmS9VpooZJQ8We1lGMPXg5bMbe/bVkTf70fbFMf0RKrQIDAQAB";
    npx:hasSignature "F40zk/co0p7hBtTcctGxpo+87Kg8Pd7CDOQb+Tac/oMtc9OlspkxUU2hfzi4VHm7CTLhhz2Ag0EcNNbVUKwvDCDOZtLvZWXNQkF/SoNQR9vQkaShAOmVndQtccuOzE/NugmJXRIqKxbYjajt9QSDNx3mdoO/lb9vMZBU/WTx+DaeFJnTxa6DfUAdCGsif/TIRu3QQtaQBaZhYWHRgFiUYLlzgTqi/eQdcjDF06zk1r1PJ3N42+Bpetsk6Ji5xJFh122slp+ZhEr3MAOJz+ddQtQpAt63QtXBjBSaz9upcWz33C8o7MK73uvt1uJ0BZV5t519NVzy/UPOGbpjN7afjg==";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2022-10-13T12:35:21.230396"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}