Mode and dynamics of vanA-type vancomycin resistance dissemination in Dutch hospitals
type: study
type: observational investigation
type: medical observational study
description: Retrospective genomic-epidemiology study of 309 vancomycin-resistant Enterococcus faecium (VRE) isolates collected in 32 Dutch hospitals (2012-2015), combining short-read and long-read whole-genome sequencing to determine whether vanA-type vancomycin resistance disseminated clonally or horizontally via plasmids and Tn1546 transposition. The study found that resistance spread through both modes, with plasmid-mediated horizontal transfer playing a substantial role.
is part of: https://w3id.org/spaces/zonmw/antibiotica-resistentie-abr/541003005
was associated with: Sergio Arredondo-Alonso
was associated with: Anita C. Schürch

Study: Mode and dynamics of vanA-type vancomycin resistance dissemination in Dutch hospitals
type: Nanopublication
has assertion: assertion
has provenance: provenance
has publication info: pubinfo
created: 2026-08-14T06:00:00Z
creator: Tobias Kuhn
license: https://creativecommons.org/publicdomain/zero/1.0/
has nanopub type: study
introduces: Mode and dynamics of vanA-type vancomycin resistance dissemination in Dutch hospitals

sig
has algorithm: RSA
signed by: Tobias Kuhn

https://w3id.org/spaces/zonmw/antibiotica-resistentie-abr/541003005
has label from api: VRE-crossword, horizontal or vertical? Transmission of vancomycin-resistant Enterococcus faecium in Dutch hospitals