Nanopublication

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ID

http://purl.org/np/RAxBBJ2WkonyQNlXfdCAOaCi64J_xqgVGeaLjVQow9M88

Formats

.trig | .trig.txt | .jelly | .jelly.txt

Content

@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAxBBJ2WkonyQNlXfdCAOaCi64J_xqgVGeaLjVQow9M88> .
@prefix sub: <http://purl.org/np/RAxBBJ2WkonyQNlXfdCAOaCi64J_xqgVGeaLjVQow9M88#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  sub:spi a <https://w3id.org/linkflows/superpattern/terms/SuperPatternInstance>;
    rdfs:label "A regulatory element within the first intron of FTO affects IRX3 and IRX5 expression during early adipogenesis";
    <https://w3id.org/linkflows/superpattern/terms/hasContextClass> <http://purl.org/np/RAtsHwzNs36rGrLnoSbGrPD351Qw033Acoe4zmdXhsYlM#early-human-adipogenesis>;
    <https://w3id.org/linkflows/superpattern/terms/hasObjectClass> <http://purl.org/np/RAwkXiTv7qCtqOYzlR6ozZRGLRtG6mlogrYdRQ1E4dRDg#expression-of-genes-IRX3-and-IRX5>;
    <https://w3id.org/linkflows/superpattern/terms/hasQualifier> <https://w3id.org/linkflows/superpattern/terms/generallyQualifier>;
    <https://w3id.org/linkflows/superpattern/terms/hasRelation> <https://w3id.org/linkflows/superpattern/terms/affects>;
    <https://w3id.org/linkflows/superpattern/terms/hasSubjectClass> <http://purl.org/np/RAxLYvJ1JrRf2JAowYGbGJleQPmqtpXnXsIvse7GmLeT8#regulatory-element-within-the-first-intron-of-FTO> .
}

sub:provenance {
  sub:activity a <https://w3id.org/linkflows/superpattern/terms/FormalizationActivity>;
    prov:used sub:quote, <https://doi.org/10.1056/NEJMoa1502214>;
    prov:wasAssociatedWith orcid:0000-0003-2432-4125 .
  
  sub:assertion prov:wasGeneratedBy sub:activity .
  
  sub:quote prov:value "The rs1421085 T-to-C single-nucleotide variant disrupts a conserved motif for the ARID5B repressor, which leads to derepression of a potent preadipocyte enhancer and a doubling of IRX3 and IRX5 expression during early adipocyte differentiation.";
    prov:wasQuotedFrom <https://doi.org/10.1056/NEJMoa1502214> .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCS1s1OiABv1mrDnFWp9ecwHdQ+UlJn6JCDYXspRsbZgsm2QAiofbnVvf6gfkcjjScd5fq3sW/W8r/o7bdafVSd6xuTG/vHrO9Ax/guPiJ6O/Z57Hk0nQy6c+l71HpaJ2BPPWKOgYiFZ/8eulmuM6BJ8TDKxoBtcqP5QbvN9KYjlQIDAQAB";
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    npx:hasSignatureTarget this: .
  
  this: dcterms:created "2021-10-27T10:22:03.671-07:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0003-2432-4125;
    npx:introduces sub:spi;
    <https://w3id.org/linkflows/reviews/isUpdateOf> <http://purl.org/np/RAxxJWyH8OdTJLs-ZY1q5jVq1OWFNOoLFvwEcUFyR8EEo>;
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    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>,
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}